Molecular-Recognition Events probed by Solid-State NMR Spectroscopy

Molecular-Recognition Events probed by Solid-State NMR Spectroscopy

Author(s): Thomas Wiegand

Publication: Bunsen-Magazin 2024, 5, 120-122

Publisher: Deutsche Bunsen-Gesellschaft für physikalische Chemie e.V., Frankfurt

Language: English

DOI: 10.26125/s8mw-1g93

Abstract: Molecular-recognition processes play a fundamental role in many disciplines of life and are essential in biology and chemistry. These events are driven by the cooperative interplay of noncovalent interactions (NCIs), such as for instance hydrogen bondings, dispersion or cation-π interactions. My group develops and applies Nuclear Magnetic Resonance (NMR) spectroscopy techniques to probe such weak chemical interactions in the solid state. This allows us to shed light on the atomic-level details of molecular recognition in rather diverse fields of biological and chemical sciences. Herein, a short summary of our current research activities we focus on with our collaboration partners is presented, namely cellular organization by phase separation, mechanochemically-induced organic reactions and interactions of substrate molecules with catalytic surfaces. Our research themes require continuous further development of the solid-state NMR methodology in concert with computational modelling.

Cite this:  T. Wiegand, Bunsen-Magazin 2024, 5, 120-122, DOI: 10.26125/s8mw-1g93

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